Administration     <b>Physiologie Recherche Master</b><br />
L'EA 4324  ORPHY (Optimisation des Régulations Physiologiques) étudie les mécanismes physiologiques participant à l’optimisation des interactions organismes-milieu  Physiology Research Master  

 


ENVIRONMENT

   METABOLISM
    (sub-cellular)

 

       CELL
      (tissue)

 

PHYSIOLOGICAL
FONCTIONS
(organ)



ADAPTATION
(organism)
OPTIMIZATION &  ENERGETIC EFFICACITY

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Home | Last publications | News

The 2010 summer school of physiology, end of fantastic experience !!!

On August 14th, 7 students and 2 faculties from UBO flew back to Towson University (Maryland, USA) after a  4-week summer school in physiology. This year main theme was "physiology of environmental adaptation".


On the syllabus,  3 weeks of lectures and lab work at Towson University followed by a 1-week trip to the Gulf of Mexico to visit the sites impacted by the Deepwater Horizon oil spill (Florida, Alabama and Louisiana).

Visit the bulletin board...

Director: Philippe Sébert
Deputy director: Guy Claireaux

The research team in physiology ORPHY is composed of 17 professors and researchers from the University of Brest. Member of the Superior Institute of Science and Technology of Brest (ISSTB), ORPHY is the foundation of research master of Physiology of Regulations


ORPHY studies the capacity to a living organism to adapt to environmental conditions and / or the effects of their changes in the aim to optimize its functions and therefore its energy expenditure.

Four organizational levels are explored

  • sub-cell
  • cell
  • organic
  • organismic

Four constraints are imposed

  • exogenous xenobiotic & pressure
  • endogenous sepsis & alteration of the endothelium

The master of Physiology of Regulations aims to train biologists in the field of integrated animal physiology: integrative analysis of the effects of environmental changes, aspects of metabolic adaptation,modeling complex biological systems ...
It permit to continue in PhD in public or private research structures or go on jobs in research engineer or study engineer in expérimentation animal.

Last publications

  • Mortelette H., Amérand A, Sébert P, Belhomme M, Calves P, Moisan C (2010) Effect of exercise training on respiration and reactive oxygen species metabolism in eel red muscle. Resp. Physiol. Neurobiol. 172: 201-205.
  • Fouchs A., Ollivier H., Haond C., Roy S., Calvès P. and Pichavant-Rafini K. (2010) Activation of the MAPKs ERK1/2 by cell swelling in turbot hepatocytes . Biol. Cell  102, 447-456.
  • Mortelette H, Moisan C, Sébert P, Belhomme M, Amérand A (2010) Fish as a model in investigations about the relationship between oxygen consumption and hydroxyl radical production in permeabilized muscle fibers. Mitochondrion 10: 555-558
  • Gutowska M.A., Melzner F., Langenbuch M., Bock C., Claireaux G. and Pörtner H.O. (2009) Acid-base regulatory of the cehalopod (Sepia offinalis) in response to environmental hypercapnia. J Comp Physiol B. DOI 10.1007/s00360-009-0412-y
  • Amérand A., Vettier A., Moisan C., Belhomme M., Sébert P. (2009) Sex-related differences in aerobic capacities and reactive oxygen species metabolism in the silver eel. Fish physiol biochem. 36(3): 741-747
  • Dupont-Prinet, A., Claireaux, G., and McKenzie, D.J. (2009). Effects of feeding and hypoxia on cardiac performance and gastrointestinal blood flow during critical speed swimming in the sea bass Dicentrarchus labrax. Comp. Biochem. Physiol. A: doi:10.1016/j.cbpa.2009.06.015.
  • Bezon E, Khalifa A, Le Gall G, Choplain J, Mansourati J, Auber Barra J (2009) Use of arterial patch to improve re-endothelialization in a sheep model of open carotid endarterectomy. An incentive to use internal thoracic artery as an on-lay patch following coronary endarterecomy? Interact Cardiovasc Thorac Surg. 8:543-547
  • Fouchs A, Ollivier H, Theron M, Roy S, Calves P, Pichavant-Rafini K. (2009) Involvement of respiratory chain in RVD process in turbot hepatocytes. Biochem Cell Biol; 87(3) 499:504.
  • Pontier J-M., Guerrero F., Castagna O. (2009) Bubble Formation and Endothelial function before and after 3 months of dive training. Aviation Space and Environmental Medicine. 80(1): 15-19
  • Sébert P, Scaion D, Belhomme M (2009). High hydrostatic pressure improves the swimming efficiency of European migrating silver eel. Resp. Physiol. Neurobiol. 165, 112-114.
  • Thioub S, Mansourati J, Corporeau C, Heylen E, Delarue J and Guerrero F. (2009) Effects of n-3 fatty acids and acute exercise on endothelium-dependent vasorelaxation in healthy rat aorta. Br J Nutr. 101(6):829-835

News

New book release

  A new book: "Comparative High Pressure Biology" edited par Philippe Sébert released in January 2010;  High pressure biology is an old, fascinating and stimulating field... > Tuesday, August 24 2010 >> read more

Bulletin board 2010

  Friday, July 16th Left Brest at 13:00 Arrived at Washington Dulles at 19:00 local time Took a chartered shuttle for a 1.5h-drive to Towson University At 24:00 got our room key and... > Monday, August 30 2010 >> read more

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